Researchers identify path to prevent cognitive decline after radiation

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester find that microglia—the brain’s immune cells—can trigger cognitive deficits after radiation exposure and may be a key target for preventing these symptoms. These findings, published in the International Journal of Radiation Oncology*Biology*Biophysics, build on previous research showing that after radiation exposure microglia damage synapses, the connections between neurons that are important for cognitive behavior and memory.

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