Early onset Merkel cell carcinoma patients could have genetic markers for other cancers

Many patients with early onset Merkel cell carcinoma have genetic variants leading to possible increased cancer risks and should receive genetic counseling and testing, according to a study.
“Merkel cell carcinoma (MCC) is a rare neuroendocrine skin cancer with approximately 3,000 U.S. cases per year,” Noreen Mohsin, MD, of the NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases, and colleagues wrote. “Understanding the etiology of MCC is crucial to improving treatments and prevention. Because patients with germline cancer predispositions often develop

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