Many patients diagnosed with MIS-C do not fit updated definition

Nearly one in five patients diagnosed with multisystem inflammatory syndrome in children based on a 2020 definition would not be diagnosed with the illness using an updated definition, researchers reported in Pediatrics.
According to the most recent CDC definition, multisystem inflammatory syndrome in children (MIS-C) “is a rare condition associated with SARS-CoV-2 [that] usually occurs 2 to 6 weeks after a child is infected … may be very mild or have no symptoms at all and may go unrecognized.”
The syndrome “causes different body parts to become inflamed, including the

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