Serum estradiol levels tied to preeclampsia risk, especially after frozen embryo transfer

Higher serum estradiol levels in early pregnancy were associated with increased risk for preeclampsia, particularly after frozen embryo transfer cycles, researchers reported in Frontiers in Endocrinology.
Yun-Chiao Hsieh, MD, adjunct attending physician in the department of obstetrics and gynecology at the National Taiwan University Hospital, and colleagues used a database from a university-affiliated IVF center from 2010 to 2020 to conduct a retrospective cohort study with data from 888 women who conceived after frozen embryo transfer. Researchers determined the adjusted effect of estradiol

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