Cholangiocarcinoma: New organ-on-chip aims at accelerating research and personalized medicine

It is only a few centimeters in size and can be held between two fingers, but hidden in the micro-channels carved inside it is a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment. This 3D model is built starting from a sample of patient’s cancer cells and thus it represents a patient-specific “organ-on-chip”: a technology made possible only through a multidisciplinary approach that merges biomedicine, physics and engineering.

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