Maladaptive proximal tubule cells may play key role in managing AKI

Maladaptive proximal tubule cells may play a key role in the long-term effect of AKI, according to data from the Kidney Precision Medicine Project.
AKI is a “major risk factor for long-term adverse outcomes, including chronic kidney disease,” researchers led by Yumeng Wen, MD, of the division of nephrology in the department of medicine at Johns Hopkins University School of Medicine in Baltimore, wrote in the study. “However, evidence for [proximal tubule] PT maladaptation and its etiological relationship with complications of AKI is lacking in humans.”

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